肝癌是常见的恶性肿瘤，其目前的治疗手段是以手术为主的综合治疗，但是术后易复发、转移，预后较差。 肿瘤干细胞学说认为只有杀灭肝癌干细胞才能从根本上治愈肝癌，因此分离和鉴定肝癌干细胞成为研 究的热点。笔者就目前的肝癌干细胞表面标志物研究进展进行综述。
Advances in research of liver cancer stem cell markers
Liver cancer is a common malignancy, and its treatment strategy is mainly surgery-based comprehensive therapy, but the prognosis is still poor because of high frequency of postoperative recurrence and metastasis. According to the cancer stem cell theory, liver cancer can be radically cured only by eradication of the liver cancer stem cells, which leads to the isolation and identification of the liver cancer stem cells to become a hot area of research. This article overviews the research progress in surface markers of liver stem cells.