目的：比较超声引导下麦默通旋切活检术与超声引导下导丝定位手术切除乳腺隐匿性肿块（NPBL）的效果，为临床手术方法的选择提供依据。方法：回顾性分析362 例行手术治疗的NPBL 患者临床资料，其中293 例超声引导下麦默通旋切活检手术（旋切组），69 例行超声引导下导丝定位开放活检术（开放组），比较两组的相关手术指标。结果：两组患者基本资料差异均无统计学意义（均P>0.05）。旋切组在手术时间、切口长度、术中出血量方面均优于开放组，手术费用明显多于开放组（均P<0.05），旋切组术后并发症发生率低于开放组，但差异无统计学意义（P>0.05）。两组手术成功率均达到100%。两组随访1~12 个月，均无肿瘤复发，开放组有长短不等的瘢痕，而旋切组瘢痕微小或不可见。结论：麦默通旋切活检术切除NPBL 安全有效，较导丝定位开放活检术出血少、手术时间短、美容效果好，但手术费用较高。
Ultrasound-guided Mammotome rotation cutting versus wire-localized surgical resection for non-palpable breast lesion
Objective: To compare the effects of ultrasound-guided Mammotome rotation cutting and wire-localized surgical resection for non-palpable breast lesion (NPBL), so as to provide the basis for procedure selection in clinical practice. Methods: The clinical data of 362 patients with NPBL undergoing surgical treatment were retrospectively analyzed. Of the patients, 293 cases underwent ultrasound-guided Mammotome procedure (rotation cutting group) and the other 69 cases underwent ultrasound-guided wire-localized surgical resection (open group). The relevant surgical parameters between the two groups were compared. Results: The general data between the two groups of patients showed no significant difference (all P>0.05). Rotation cutting group was superior to open group in variables of operative time, length of incision, and intraoperative blood loss, but the surgical cost in rotation cutting group was significantly higher than that in open group (all P<0.05). The incidence of postoperative complications in rotation cutting group was lower than that in open group, but the difference was not significant (P>0.05). The success rate of surgery in both groups reached 100%. No tumor recurrence occurred in the two groups during followed up for 1 month to 12 months, and evident scars of different sizes were seen in open group, while scars were small or invisible in rotation cutting group. Conclusion: Mammotome rotation cutting for NPBL is safe and effective, and has less bleeding, shorter operative time and favorable cosmetic results, but higher cost compared to wire-localized surgical resection.