临床研究(Clinical Research)

胰腺混合性腺泡- 神经内分泌癌1 例报道及文献复习

Published at: 2016年第25卷第3期

荣华 1 , 李民 1 , 王思珍 1 , 申荣喜 1 , 朱道俊 1 , 王新波 1
1 南京大学医学院附属金陵医院/ 中国人民解放军南京军区南京总医院 普通外科研究所,江苏 南京 210002
通讯作者 新波 王 Email: wxinbo@hotmail.com
DOI: 10.3978/j.issn.1005-6947.10.3978/j.issn.1005-6947.2016.03.018
基金:

摘要

目的:探讨胰腺混合性腺泡- 神经内分泌癌(MANEC)的临床病理特征、鉴别诊断和治疗方法。方法:回顾性分析收治的1 例胰腺MANEC 患者的临床资料,结合国内外文献,总结该病的临床特点、病理特征、鉴别诊断和治疗方法。结果:该患者术前影像学检查提示十二指肠降部肿瘤,行手术治疗,术后病理提示胰腺MANEC。术后患者顺利出院,20 个月后复查CT 提示肿瘤无复发转移。结论:胰腺MANEC 是非常罕见的肿瘤,常无典型的症状,最终需要病理确诊。预后至今不清楚,但是早期的手术治疗能显著提高总的生存期。


Mixed acinar-neuroendocrine carcinoma of the pancreas: a case report and literature review

Abstract

Objective: To investigate the clinicopathologic features, and differential diagnosis and treatment method of the mixed acinar-neuroendocrine carcinoma (MANEC) of the pancreas. Methods: The clinical record of one patient with MANEC was retrospectively analyzed, in combination with domestic and foreign literature review, to summarize the clinical features, pathological features, differential diagnosis and treatment method for this disease. Results: Preoperative imaging examinations suggested that the patient had a tumor of descending duodenum, and then the patient underwent surgical treatment. The pathological diagnosis was pancreatic MANEC. The patient was discharged after operation and no tumor recurrence or metastasis was noted 20 months later. Conclusion: MANEC of the pancreas is extremely rare, usually without typical symptoms, and the final diagnosis depends on pathological findings. Its prognosis remains unclear to date, but early surgical treatment can significantly improve the overall survival.


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引用

引用本文: 华 荣, 民 李, 思珍 王, 荣喜 申, 道俊 朱, 新波 王. 胰腺混合性腺泡- 神经内分泌癌1 例报道及文献复习[J]. 中国普通外科杂志, 2016, 25(3): 413-417.
Cite this article as: RONG Hua, LI Min, WANG Sizhen, SHEN Rongxi, ZHU Daojun, WANG Xinbo . Mixed acinar-neuroendocrine carcinoma of the pancreas: a case report and literature review[J]. Chin J Gen Surg, 2016, 25(3): 413-417.