述评(Commentary)

胰腺癌外科治疗的现状、存在问题与展望

Published at: 2016年第25卷第9期

杨尹默 1
1 北京大学第一医院 外科,北京 100034
通讯作者 尹默 杨 Email: yangyinmo@263.net
DOI: 10.3978/j.issn.1005-6947.10.3978/j.issn.1005-6947.2016.09.001
基金:

摘要

胰腺癌在所有消化道肿瘤中预后最差,治疗极具挑战性。胰腺癌的治疗模式正在由“surgery first”转变为“MDT”;对于可能切除的胰腺癌,提倡开展新辅助治疗,以提高R0切除率;在临床研究之外,提倡进行标准范围的淋巴清扫;胰瘘是胰十二指肠切除术后最为严重的并发症,不同胰腺与消化道重建方式对胰瘘的影响并无显著性差异,应重视提高吻合质量以降低胰瘘发生率。


Surgical managements of pancreatic cancer: current status and future directions

Abstract

The prognosis of patients with pancreatic carcinoma is the poorest of all the digestive system cancers, and the managements are very challenging. Now the treatment mode of pancreatic carcinoma is converting into “MDT” from “surgery first”. Neoadjuvant therapy is advocated for borderline resectable pancreatic carcinoma so as to increase rates of R0 resection. The standard lymphadenectomy is recommended in routine clinical practice except in special clinical trials. Pancreatic fistula is the severest complication of pancreatoduodenectomy. There are no significant differences in relation of methods of pancreatoenteric anastomosis to the occurrence of postoperative pancreatic fistula, so the quality of the anatomosis and the technical skills should be emphasized in order to decrease the incidence of pancreatic fistula.


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引用

引用本文: 尹默 杨. 胰腺癌外科治疗的现状、存在问题与展望 [J]. 中国普通外科杂志, 2016, 25(9): 1231-1235.
Cite this article as: YANG Yinmo . Surgical managements of pancreatic cancer: current status and future directions[J]. Chin J Gen Surg, 2016, 25(9): 1231-1235.