目的：探讨局部肿胀麻醉技术在乳腺多发实性肿块Mammotome微创旋切术中的临床应用效果。方法：随机选择2010年6月—2012年7月98例施行乳腺多发实性肿块Mammotome微创旋切术患者，其中49例行传统局部浸润麻醉（对照组），另49例行局部肿胀麻醉（观察组）；对比两组患者的主要临床指标。结果：两组患者在年龄、肿块直径及肿块个数上的差异无统计学意义（均P>0.05）。与对照组比较，观察组平均麻醉实施时间缩短（16.10 min vs. 31.41 min）、手术时间减少（39.47 min vs. 62.53 min）、麻醉剂降低（0.20 mg vs. 0.31 mg）、麻醉效果良好率增高（96% vs. 82%）、麻醉不良反应发生率低（0% vs. 12%）、手术并发症发生率低（4% vs. 18%），差异均有统计学意义（均P<0.05）。结论：在乳腺多发实性肿块Mammotome微创旋切术中应用局部肿胀麻醉技术安全有效，临床效果显著，值得推荐使用。
Application of local tumescent anesthesia technique in minimally invasive Mammotome rotation cutting for multiple solid breast lesions
Objective: To investigate the clinical efficacy of using local tumescent anesthesia technique in minimally invasive Mammotome rotation cutting for multiple solid breast lesions. Methods: Ninety-eight patients with multiple solid breast lesions undergoing minimally invasive Mammotome rotation cutting from June 2010 to July 2012 were randomly enrolled. Of the patients, 49 cases underwent surgery under traditional local infiltration anesthesia (control group), and the other 49 cases underwent surgery with local tumescent technique (observation group). The main clinical variables between the two groups of patients were compared. Results: There was no difference in age, tumor size and tumor number between the two groups of patients (all P>0.05). In observation group compared with control group, the average time for anesthesia (16.10 min vs. 31.41 min) and operative time (39.47 min vs. 62.53 min) were shortened, the anesthestic dose (0.20 mg vs. 0.31 mg) was reduced, the good anesthetic effect rate (96% vs. 82%) was increased, and incidence of anesthesia adverse reactions (0% vs. 12%) as well as incidence of operative complications (4% vs. 18%) were decreased. All the differences had statistical significance (all P<0.05). Conclusion: Using local tumescent anesthesia technique in minimally invasive Mammotome rotation cutting for multiple solid breast lesions is safe and effective, with significant clinical efficacy. It is recommended to be used in clinical practice.